NSTL国家科技图书文献中心

1. STAT3 mediates ECM stiffness-dependent progression in ovarian cancer NSTL国家科技图书文献中心

Chenchen, Sun | Xueqian, Qian ... - 《Molecular and Cellular Biochemistry》 - 2025,480(1) - 607～620 - 共14页

摘要： crucial regulatory role of STAT3* in the malignant* | the relationship between STAT3* and matrix stiffness* | of STAT3* in vitro under different matrix* | confirmed the differential expression of STAT3/p-STAT3* not* | verified that STAT3* was a mechanically responsive gene*

关键词： Biomechanics | ECM | Ovarian cancer | STAT3 | Stiffness

2. The transcription factor STAT3 and aging: an intermediate medium NSTL国家科技图书文献中心

Shi, Min | Li, Honyu ... - 《Biogerontology》 - 2025,26(2) - 共14页

摘要：, leading to a variety of aging-related diseases. STAT3* is* | cause the activation of STAT3* to varying degrees* | aging process. Drugs targeting STAT3* can treat* | role of STAT3* signaling factors in the pathogenesis* | regulatory role of STAT3* in senescence related diseases is*

关键词： Aging mechanism | STAT3 | Aging-related diseases

3. Lactate induces oxidative phosphorylation in osteoblasts via Gpr81-Stat3 signaling NSTL国家科技图书文献中心

Hu, Xiping | Shen, Jin ... - 《Cellular Signalling》 - 2025,133 - 共14页

摘要： and RNA-sequencing analysis revealed that Stat3 | lactate activated the Jak2-Stat3-Y705 and Akt-Stat3S727 | signaling. Inhibition of Jak2-Stat3-Y705 signaling by | Gpr81-Jak2-Stat3-Y705 and Gpr81-Akt-Stat3S727 | as well as OXPHOS through the activation of Stat3

关键词： Lactate | Gpr81 | Oxidative phosphorylation | Osteoblast differentiation | Stat3 signaling

4. Transcription Factor STAT3-Activated LDHB Promotes Tumor Properties of Endometrial Cancer Cells by Inducing MDH2 Expression NSTL国家科技图书文献中心

Shen, Li | Wang, Juan ... - 《Molecular biotechnology》 - 2025,67(2) - 562～574 - 共13页

摘要： transcription 3 (STAT3), LDHB, and MDH2 were predicted through | property of Ishikawa cells in vivo. STAT3* bound to the* | promoter region of LDHB, and STAT3* silencing-induced* | effects on EC cell phenotypes. STAT3-activated LDHB | The pathogenesis of endometrial cancer (EC

关键词： EC | STAT3 | LDHB | MDH2

5. Isoliquiritigenin attenuates tumor progression and PD-L1 expression by inhibiting the phosphorylation of STAT3 in melanoma NSTL国家科技图书文献中心

Zeng, Haiyan | Guo, Aoxiang ... - 《Medical oncology.》 - 2025,42(4) - Article: 118～Article: 118 - 共10页

摘要： of programmed cell death ligand 1 (PD-L1), STAT3 | repress the expression of PD-L1 and STAT3 | with the expression of STAT3. Furthermore, the STAT3 | expression by repressing the phosphorylation of STAT3 | Isoliquiritigenin (ISL) has been reported with

关键词： Isoliquiritigenin | STAT3 phosphorylation | PD-L1 | Melanoma

6. NLRC5 in Macrophages Promotes Atherosclerosis in Acute Coronary Syndrome by Regulating STAT3 Expression NSTL国家科技图书文献中心

Chen, Jun | Chen, Guoqin ... - 《Cardiovascular toxicology.》 - 2025,25(3) - 365～378 - 共14页

摘要： M1 phenotype. STAT3* was identified as a target of* | STAT3 ubiquitination. Methylation promoted NLRC5 DNA | . STAT3* reduced the effects of sh-NLRC5-mediated M1/M2* | coronary syndrome by regulating STAT3* expression. This* | The mortality rate of cardiovascular and

关键词： NLRC5 | STAT3 | Atherosclerosis | Ubiquitination | Methylation

Saadh, Mohamed J. | Abd Hamid, Junainah ... - 《Pathology Research and Practice》 - 2025,266 - 155810～155810 - 共10页

摘要： of transcription 3 (STAT3) is essential for | tumor environment, STAT3* is widely overactivated in* | influence important signaling pathways such as STAT3 | comprehensive overview of the interaction between the STAT3 | Colorectal cancer (CRC) is globally ranked as

关键词： LncRNAs | STAT3 | Colorectal cancer | MiRNAs | Immune evasion

8. Granulocyte Colony Stimulating Factor Enhances Decidualization Process of Endometrial Stromal Cells Through STAT3/HOXA10 Axis NSTL国家科技图书文献中心

Zhang, Huakun | Wu, Zhengzhong ... - 《Advanced Biology》 - 2025,9(2) - 共9页

摘要： transducer and activator of transcription 3 (STAT3) and the | STAT3/HOXA10 axis in the action of G-CSF. Results: G | enhanced STAT3* activation during decidualization* | induction. STAT3* inhibition diminished the effects of G* | that G-CSF increased Hoxa10 expression in a STAT3

关键词： decidualization | G-CSF | HOXA10 | STAT3 | THESCs | G‐CSF

9. STING coordinates resolution of inflammation during wound repair by modulating macrophage trafficking through STAT3 NSTL国家科技图书文献中心

Chen, Cheng | Cai, Xin ... - 《Journal of Leukocyte Biology》 - 2025,117(3) - qiae175～qiae175 - 共12页

摘要： capacity through STAT3* activation. Specifically, STING* | STING-STAT3-chemokine signaling combine to delay | STAT3 to orchestrate inflammatory resolution necessary | regulates the macrophage trafficking through STAT3* in* | Efficient cutaneous wound healing requires a

关键词： inflammation | macrophages | STAT3 | STING | wound healing

10. Realgar induces apoptosis by inhibiting glycolysis via regulating STAT3 in myelodysplastic syndrome NSTL国家科技图书文献中心

Xue, Tingting | Tao, Yuchen ... - 《Journal of Ethnopharmacology》 - 2025,341 - Article 119339～Article 119339 - 共14页

摘要： involving STAT3, glycolysis, and apoptosis. Hematoxylin | , CETSA, qRT-PCR, WB, apoptosis assays, and STAT3 | inhibits STAT3* expression. Further investigation using* | directly bind to STAT3. In MDS mice, realgar treatment | demonstrated that realgar regulates the STAT3* pathway*

摘要： crucial regulatory role of STAT3* in the malignant* | the relationship between STAT3* and matrix stiffness* | of STAT3* in vitro under different matrix* | confirmed the differential expression of STAT3/p-STAT3* not* | verified that STAT3* was a mechanically responsive gene*

关键词： Biomechanics | ECM | Ovarian cancer | STAT3 | Stiffness

摘要：, leading to a variety of aging-related diseases. STAT3* is* | cause the activation of STAT3* to varying degrees* | aging process. Drugs targeting STAT3* can treat* | role of STAT3* signaling factors in the pathogenesis* | regulatory role of STAT3* in senescence related diseases is*

关键词： Aging mechanism | STAT3 | Aging-related diseases

摘要： and RNA-sequencing analysis revealed that Stat3 | lactate activated the Jak2-Stat3-Y705 and Akt-Stat3S727 | signaling. Inhibition of Jak2-Stat3-Y705 signaling by | Gpr81-Jak2-Stat3-Y705 and Gpr81-Akt-Stat3S727 | as well as OXPHOS through the activation of Stat3

关键词： Lactate | Gpr81 | Oxidative phosphorylation | Osteoblast differentiation | Stat3 signaling

摘要： transcription 3 (STAT3), LDHB, and MDH2 were predicted through | property of Ishikawa cells in vivo. STAT3* bound to the* | promoter region of LDHB, and STAT3* silencing-induced* | effects on EC cell phenotypes. STAT3-activated LDHB | The pathogenesis of endometrial cancer (EC

关键词： EC | STAT3 | LDHB | MDH2

摘要： of programmed cell death ligand 1 (PD-L1), STAT3 | repress the expression of PD-L1 and STAT3 | with the expression of STAT3. Furthermore, the STAT3 | expression by repressing the phosphorylation of STAT3 | Isoliquiritigenin (ISL) has been reported with

关键词： Isoliquiritigenin | STAT3 phosphorylation | PD-L1 | Melanoma

摘要： M1 phenotype. STAT3* was identified as a target of* | STAT3 ubiquitination. Methylation promoted NLRC5 DNA | . STAT3* reduced the effects of sh-NLRC5-mediated M1/M2* | coronary syndrome by regulating STAT3* expression. This* | The mortality rate of cardiovascular and

关键词： NLRC5 | STAT3 | Atherosclerosis | Ubiquitination | Methylation

摘要： of transcription 3 (STAT3) is essential for | tumor environment, STAT3* is widely overactivated in* | influence important signaling pathways such as STAT3 | comprehensive overview of the interaction between the STAT3 | Colorectal cancer (CRC) is globally ranked as

关键词： LncRNAs | STAT3 | Colorectal cancer | MiRNAs | Immune evasion

摘要： transducer and activator of transcription 3 (STAT3) and the | STAT3/HOXA10 axis in the action of G-CSF. Results: G | enhanced STAT3* activation during decidualization* | induction. STAT3* inhibition diminished the effects of G* | that G-CSF increased Hoxa10 expression in a STAT3

关键词： decidualization | G-CSF | HOXA10 | STAT3 | THESCs | G‐CSF

摘要： capacity through STAT3* activation. Specifically, STING* | STING-STAT3-chemokine signaling combine to delay | STAT3 to orchestrate inflammatory resolution necessary | regulates the macrophage trafficking through STAT3* in* | Efficient cutaneous wound healing requires a

关键词： inflammation | macrophages | STAT3 | STING | wound healing

摘要： involving STAT3, glycolysis, and apoptosis. Hematoxylin | , CETSA, qRT-PCR, WB, apoptosis assays, and STAT3 | inhibits STAT3* expression. Further investigation using* | directly bind to STAT3. In MDS mice, realgar treatment | demonstrated that realgar regulates the STAT3* pathway*

关键词： Myelodysplastic syndrome | realgar | Glycolysis | STAT3 | apoptosis

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： crucial regulatory role of STAT3 in the malignant | the relationship between STAT3 and matrix stiffness | of STAT3 in vitro under different matrix | confirmed the differential expression of STAT3/p-STAT3 not | verified that STAT3 was a mechanically responsive gene

关键词： Biomechanics | ECM | Ovarian cancer | STAT3 | Stiffness

摘要：, leading to a variety of aging-related diseases. STAT3 is | cause the activation of STAT3 to varying degrees | aging process. Drugs targeting STAT3 can treat | role of STAT3 signaling factors in the pathogenesis | regulatory role of STAT3 in senescence related diseases is

关键词： Aging mechanism | STAT3 | Aging-related diseases

摘要： and RNA-sequencing analysis revealed that Stat3 | lactate activated the Jak2-Stat3-Y705 and Akt-Stat3S727 | signaling. Inhibition of Jak2-Stat3-Y705 signaling by | Gpr81-Jak2-Stat3-Y705 and Gpr81-Akt-Stat3S727 | as well as OXPHOS through the activation of Stat3

关键词： Lactate | Gpr81 | Oxidative phosphorylation | Osteoblast differentiation | Stat3 signaling

摘要： transcription 3 (STAT3), LDHB, and MDH2 were predicted through | property of Ishikawa cells in vivo. STAT3 bound to the | promoter region of LDHB, and STAT3 silencing-induced | effects on EC cell phenotypes. STAT3-activated LDHB | The pathogenesis of endometrial cancer (EC

关键词： EC | STAT3 | LDHB | MDH2

摘要： of programmed cell death ligand 1 (PD-L1), STAT3 | repress the expression of PD-L1 and STAT3 | with the expression of STAT3. Furthermore, the STAT3 | expression by repressing the phosphorylation of STAT3 | Isoliquiritigenin (ISL) has been reported with

关键词： Isoliquiritigenin | STAT3 phosphorylation | PD-L1 | Melanoma

摘要： M1 phenotype. STAT3 was identified as a target of | STAT3 ubiquitination. Methylation promoted NLRC5 DNA | . STAT3 reduced the effects of sh-NLRC5-mediated M1/M2 | coronary syndrome by regulating STAT3 expression. This | The mortality rate of cardiovascular and

关键词： NLRC5 | STAT3 | Atherosclerosis | Ubiquitination | Methylation

摘要： of transcription 3 (STAT3) is essential for | tumor environment, STAT3 is widely overactivated in | influence important signaling pathways such as STAT3 | comprehensive overview of the interaction between the STAT3 | Colorectal cancer (CRC) is globally ranked as

关键词： LncRNAs | STAT3 | Colorectal cancer | MiRNAs | Immune evasion

摘要： transducer and activator of transcription 3 (STAT3) and the | STAT3/HOXA10 axis in the action of G-CSF. Results: G | enhanced STAT3 activation during decidualization | induction. STAT3 inhibition diminished the effects of G | that G-CSF increased Hoxa10 expression in a STAT3

关键词： decidualization | G-CSF | HOXA10 | STAT3 | THESCs | G‐CSF

摘要： capacity through STAT3 activation. Specifically, STING | STING-STAT3-chemokine signaling combine to delay | STAT3 to orchestrate inflammatory resolution necessary | regulates the macrophage trafficking through STAT3 in | Efficient cutaneous wound healing requires a

关键词： inflammation | macrophages | STAT3 | STING | wound healing

摘要： involving STAT3, glycolysis, and apoptosis. Hematoxylin | , CETSA, qRT-PCR, WB, apoptosis assays, and STAT3 | inhibits STAT3 expression. Further investigation using | directly bind to STAT3. In MDS mice, realgar treatment | demonstrated that realgar regulates the STAT3 pathway

关键词： Myelodysplastic syndrome | realgar | Glycolysis | STAT3 | apoptosis

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： crucial regulatory role of STAT3* in the malignant* | the relationship between STAT3* and matrix stiffness* | of STAT3* in vitro under different matrix* | confirmed the differential expression of STAT3/p-STAT3* not* | verified that STAT3* was a mechanically responsive gene*

摘要：, leading to a variety of aging-related diseases. STAT3* is* | cause the activation of STAT3* to varying degrees* | aging process. Drugs targeting STAT3* can treat* | role of STAT3* signaling factors in the pathogenesis* | regulatory role of STAT3* in senescence related diseases is*

摘要： transcription 3 (STAT3), LDHB, and MDH2 were predicted through | property of Ishikawa cells in vivo. STAT3* bound to the* | promoter region of LDHB, and STAT3* silencing-induced* | effects on EC cell phenotypes. STAT3-activated LDHB | The pathogenesis of endometrial cancer (EC

摘要： M1 phenotype. STAT3* was identified as a target of* | STAT3 ubiquitination. Methylation promoted NLRC5 DNA | . STAT3* reduced the effects of sh-NLRC5-mediated M1/M2* | coronary syndrome by regulating STAT3* expression. This* | The mortality rate of cardiovascular and

摘要： of transcription 3 (STAT3) is essential for | tumor environment, STAT3* is widely overactivated in* | influence important signaling pathways such as STAT3 | comprehensive overview of the interaction between the STAT3 | Colorectal cancer (CRC) is globally ranked as

摘要： transducer and activator of transcription 3 (STAT3) and the | STAT3/HOXA10 axis in the action of G-CSF. Results: G | enhanced STAT3* activation during decidualization* | induction. STAT3* inhibition diminished the effects of G* | that G-CSF increased Hoxa10 expression in a STAT3

摘要： capacity through STAT3* activation. Specifically, STING* | STING-STAT3-chemokine signaling combine to delay | STAT3 to orchestrate inflammatory resolution necessary | regulates the macrophage trafficking through STAT3* in* | Efficient cutaneous wound healing requires a

摘要： involving STAT3, glycolysis, and apoptosis. Hematoxylin | , CETSA, qRT-PCR, WB, apoptosis assays, and STAT3 | inhibits STAT3* expression. Further investigation using* | directly bind to STAT3. In MDS mice, realgar treatment | demonstrated that realgar regulates the STAT3* pathway*